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MK-4827 Racemate

Catalog No. T22988   CAS 1038915-75-1
Synonyms: Niraparib Racemate, 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide

MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.

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MK-4827 Racemate Chemical Structure
MK-4827 Racemate, CAS 1038915-75-1
Pack Size Availability Price/USD Quantity
1 mg In stock $ 45.00
2 mg In stock $ 63.00
5 mg In stock $ 89.00
10 mg In stock $ 156.00
25 mg In stock $ 297.00
50 mg In stock $ 518.00
100 mg In stock $ 698.00
1 mL * 10 mM (in DMSO) In stock $ 121.00
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Purity: 99.47%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
Targets&IC50 PARP2:2.1 nM, PARP1:3.8 nM
Synonyms Niraparib Racemate, 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide
Molecular Weight 320.39
Formula C19H20N4O
CAS No. 1038915-75-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/ml (187.27 mM)

TargetMolReferences and Literature

1. Schäfer P, Palacin T, Sidera M, Fletcher SP. Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates. Nat Commun. 2017 Jun 13;8:15762.

Related compound libraries

This product is contained In the following compound libraries:
DNA Damage & Repair Compound Library Bioactive Compound Library Anti-Prostate Cancer Compound Library Bioactive Compounds Library Max Epigenetics Compound Library Inhibitor Library Anti-Pancreatic Cancer Compound Library Anti-Cancer Compound Library Anti-Ovarian Cancer Compound Library

Related Products

Related compounds with same targets
Rucaparib monocamsylate 4beta-Hydroxywithanolide E Furanodiene Niraparib (R-enantiomer) Niraparib hydrochloride RBN-2397 Euchrestaflavanone B G007-LK

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Keywords

MK-4827 Racemate 1038915-75-1 Chromatin/Epigenetic DNA Damage/DNA Repair PARP MK4827 Racemate Niraparib Racemate MK 4827 Racemate 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide inhibitor inhibit

 

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