Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MN58b is a selective inhibitor of choline kinase α (CHKα).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 311.00 | |
5 mg | In stock | $ 759.00 | |
10 mg | In stock | $ 987.00 | |
25 mg | In stock | $ 1,550.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | In stock | $ 2,790.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 957.00 |
Description | MN58b is a selective inhibitor of choline kinase α (CHKα). |
In vitro | MN58b (1-5 μM; 72 hours; SK-PC-1, Suit2 008, IMIM-PC2, and RWP-1 cells) has a marked effect on colony formation at 1 μM, and growth is completely abolished at 5 μM in all the cell lines[1] |
In vivo | MN58b treatment significantly decreases phosphomonoesters in both HT29 and MDA-MB-231 xenografts. Phosphocholine levels are found to correlate with choline kinase activities[2]. |
Molecular Weight | 640.49 |
Formula | C32H40Br2N4 |
CAS No. | 203192-01-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6.41 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MN58b 203192-01-2 Apoptosis Neuroscience AChR inhibit Inhibitor MN-58b inhibitor