Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MZP-55 is a selective BRD3/4 degrader based on PROTAC technology(Brd4BD2 with Kd of 8 nM)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 456.00 | |
10 mg | Inquiry | $ 698.00 | |
25 mg | Inquiry | $ 1,320.00 | |
50 mg | Inquiry | Inquiry | |
100 mg | Inquiry | Inquiry | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 497.00 |
Description | MZP-55 is a selective BRD3/4 degrader based on PROTAC technology(Brd4BD2 with Kd of 8 nM) |
Targets&IC50 | BRD4 BD2:(kd)8 nM |
In vitro | MZP-55 binds to VHL-EloC-EloB protein (VCB) with a Kd of 105 ± 24 nM. MZP-55 shows an inhibitory activity against MV4;11 and HL60 cells, with pEC50s of 7.31 ± 0.03 and 6.57 ± 0.02, respectively[1]. |
Molecular Weight | 1080.73 |
Formula | C57H70ClN7O10S |
CAS No. | 2010159-48-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (46.27 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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MZP-55 2010159-48-3 Chromatin/Epigenetic Epigenetic Reader Domain MZP55 MZP 55 inhibitor inhibit