Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 30.00 | |
5 mg | In stock | $ 47.00 | |
10 mg | In stock | $ 76.00 | |
25 mg | In stock | $ 147.00 | |
50 mg | In stock | $ 228.00 | |
100 mg | In stock | $ 343.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 52.00 |
Description | Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity. |
In vitro | Mavacoxib is cytotoxic to a panel of human and canine osteosarcoma, mammary and bladder carcinoma cancer cell lines;?that it can induce apoptosis and inhibit the migration of these cells.?Mavacoxib can exert these effects independently of elevated COX-2 expression[1].Mavacoxib has a direct cell killing effect on cancer cells, increases apoptosis in cancer cells in a manner that may be independent of caspase activity, and has an inhibitory effect on cell migration.?Importantly, that cancer stem cells derived from osteosarcoma cell lines are sensitive to the cytotoxic effect of mavacoxib[2] |
Molecular Weight | 385.34 |
Formula | C16H11F4N3O2S |
CAS No. | 170569-88-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (58.39 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Mavacoxib 170569-88-7 Immunology/Inflammation Neuroscience COX Cyclooxygenase Inhibitor inhibit inhibitor