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Meloxicam

Catalog No. T0826   CAS 71125-38-7
Synonyms: Movalis, Mobic, Metacam

Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of meloxicam is as a Cyclooxygenase Inhibitor. The chemical classification of meloxicam is Nonsteroidal Anti-inflammatory Compounds.

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Meloxicam Chemical Structure
Meloxicam, CAS 71125-38-7
Pack Size Availability Price/USD Quantity
100 mg In stock $ 33.00
200 mg In stock $ 45.00
500 mg In stock $ 83.00
1 mL * 10 mM (in DMSO) In stock $ 37.00
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Purity: 99.89%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of meloxicam is as a Cyclooxygenase Inhibitor. The chemical classification of meloxicam is Nonsteroidal Anti-inflammatory Compounds.
Targets&IC50 COX-2:0.49 µM, COX-1:36.6 µM
Synonyms Movalis, Mobic, Metacam
Molecular Weight 351.4
Formula C14H13N3O4S2
CAS No. 71125-38-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 28 mg/mL (79.7 mM)

TargetMolReferences and Literature

1. Goldman AP, et al. Carcinogenesis, 1998, 19(12), 2195-2199. 2. Naruse T, et al. Carcinogenesis, 2006, 27(3), 584-592. 3. de Grauw JC, et al. Equine Vet J, 2009, 41(7), 693-699. 4. Little D, et al. Am J Vet Res, 2007, 68(6), 614-624. 5. Jones CJ, et al. Am J Vet Res, 2002, 63(11), 1527-1531. 6. Iturriaga MP, et al. Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells. Oncol Lett. 2017 Aug;14(2):2198-2206. 7. Fikry EM, et al. Rutin and meloxicam attenuate paw inflammation in mice: Affecting sorbitol dehydrogenase activity. J Biochem Mol Toxicol. 2018 Feb;32(2). 8. Song Z, He Z, Meng L, et al. RNA-seq profiles of LPS-induced transcriptional changes in LBP-deficient rat and its possible implications for the liver dysregulation during sepsis[J]. 2020.

TargetMolCitations

1. He Z, Song Z, Meng L, et al. Lipopolysaccharide-Induced Transcriptional Changes in LBP-Deficient Rat and Its Possible Implications for Liver Dysregulation during Sepsis. Journal of Immunology Research. 2021, 2021. 2. Bi X, Yan X, Jiang B, et al. Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses. Toxicology and Applied Pharmacology. 2021: 115778.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Neurodegenerative Disease Compound Library Anti-Cancer Clinical Compound Library Anti-Cancer Approved Drug Library FDA-Approved & Pharmacopeia Drug Library Cardiotoxicity Compound Library Bioactive Compounds Library Max Immunology/Inflammation Compound Library FDA-Approved Drug Library Human Metabolite Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Meloxicam 71125-38-7 Apoptosis Autophagy Immunology/Inflammation Neuroscience COX Inhibitor inhibit Movalis Cyclooxygenase Mobic Metacam inhibitor

 

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