Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mesaconine is an ingredient from Aconitum carmichaelii Debx.. Mesaconine has a cardiac effect and anti-NF-κB activity. Mesaconine may be part of the material basis of Mahuang Fuzi Xixin decoction on anti-inflammation and immune suppression.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 228.00 | |
5 mg | In stock | $ 559.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 654.00 |
Description | Mesaconine is an ingredient from Aconitum carmichaelii Debx.. Mesaconine has a cardiac effect and anti-NF-κB activity. Mesaconine may be part of the material basis of Mahuang Fuzi Xixin decoction on anti-inflammation and immune suppression. |
In vitro | The anti-inflammatory effect of SFI was verified in vitro with endothelial cells. After detecting the cell viability, the expression of interleukin-6 (IL-6), inhibitor of nuclear factor kappa-B kinase (IKK), phosphorylated IKK, phosphorylated NF-κB and phosphorylated IκB-α± from the supernatant were determined. SFI could significantly suppress inflammatory responses, and the mechanism may be via an NF-κB-dependent pathway. Mesaconine is the first reported SFI compounds to have NF-κB inhibitor activity[1]. |
Source |
Molecular Weight | 485.57 |
Formula | C24H39NO9 |
CAS No. | 6792-09-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (113.27 mM)
You can also refer to dose conversion for different animals. More
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Mesaconine 6792-09-2 Immunology/Inflammation NF-Κb NF-κB IL Receptor Inhibitor inhibit inhibitor