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Methyl cinnamate

Catalog No. T5552   CAS 103-26-4

Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.

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Methyl cinnamate Chemical Structure
Methyl cinnamate, CAS 103-26-4
Pack Size Availability Price/USD Quantity
500 mg In stock $ 42.00
1 mL * 10 mM (in DMSO) In stock $ 46.00
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Purity: 99.95%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
In vitro At 1-3000 μmol/L, the E-isomer of methyl cinnamate (E-MC) concentration-dependently relaxed endothelium-intact aortic preparations that had been precontracted with phenylephrine (PHE; 1 μmol/L), with an IC50 value (geometric mean) of 877.6 μmol/L (95% confidence interval (CI) 784.1-982.2 μmol/L). Over the concentration range 1-3000 μmol/L, E-MC relaxed K(+) -induced contractions in mesenteric artery preparations (IC50 314.5 μmol/L; 95% CI 141.9-697.0 μmol/L) with greater potency than in aortic preparations (IC50 1144.7 μmol/L; 95% CI 823.2-1591.9 μmol/L).
Source
Molecular Weight 162.19
Formula C10H10O2
CAS No. 103-26-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: Insoluble

DMSO: 30 mg/mL (184.97 mM)

TargetMolReferences and Literature

1. Vasconcelos-Silva AA, et al. Vasorelaxation induced by methyl cinnamate, the major constituent of the essential oil of Ocimum micranthum, in rat isolated aorta. Clin Exp Pharmacol Physiol. 2014 Oct;41(10):755-62.

Related compound libraries

This product is contained In the following compound libraries:
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Keywords

Methyl cinnamate 103-26-4 Chromatin/Epigenetic Microbiology/Virology PI3K/Akt/mTOR signaling Proteases/Proteasome Tyrosinase Antibacterial AMPK inhibit Bacterial Methyl 3-phenylpropenoate CaMKK2 3T3-L1 SREBP-1 Inhibitor activation AMP-activated protein kinase cells PPARγ natural flavor preadipocytes C/EBPα antimicrobial inhibitor

 

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