Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 33.00 | |
5 mg | In stock | $ 68.00 | |
10 mg | In stock | $ 97.00 | |
25 mg | In stock | $ 158.00 | |
50 mg | In stock | $ 239.00 | |
100 mg | In stock | $ 319.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 78.00 |
Description | Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA. |
In vitro | Immunocytochemical methods were used to measure the accumulation of phosphorylated H2AX (γH2AX) foci following ionizing radiation (IR) in patient-derived lymphoblastoid cells exposed to methylproamine. Pulsed field gel electrophoresis DNA damage and repair assays were performed to directly interrogate the action of methylproamine on DNA in irradiated cells.Methylproamine-treated cells had fewer γH2AX foci after IR compared to untreated cells. Also, the presence of methylproamine decreased the amount of lower molecular weight DNA entering the gel[2]. |
Molecular Weight | 465.59 |
Formula | C28H31N7 |
CAS No. | 188247-01-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 41 mg/mL (88.06 mM)
You can also refer to dose conversion for different animals. More
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Methylproamine 188247-01-0 Others Inhibitor Radioprotector DNA/RNA Synthesis inhibit DNA double-strand inhibitor