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Mirodenafil dihydrochloride

Catalog No. TQ0126 CAS 862189-96-6

Synonyms: SK-3530 dihydrochloride

Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Mirodenafil dihydrochloride Chemical Structure

Mirodenafil dihydrochloride, CAS 862189-96-6

Pack Size	Availability	Price/USD
5 mg	In stock	$ 44.00
10 mg	In stock	$ 72.00
25 mg	In stock	$ 136.00
50 mg	In stock	$ 222.00
100 mg	In stock	$ 355.00
500 mg	In stock	$ 842.00
1 mL * 10 mM (in DMSO)	In stock	$ 59.00

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Purity: 99.46%

Purity: 99.27%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.

In vivo

Mirodenafil, in doses of 50 or 100 mg, significantly improved erectile function and was well tolerated in a representative population of Korean men with broad-spectrum ED of various etiologies and severities [1]. The concurrent administration of mirodenafil with alcohol was not associated with clinically significant hemodynamic changes in these healthy male volunteers in Korea. The pharmacokinetics of mirodenafil were not significantly altered by this concurrent administration. Mirodenafil administered with alcohol had a tolerability profile comparable to that of mirodenafil alone [2].

Synonyms	SK-3530 dihydrochloride
Molecular Weight	604.59
Formula	C26H39Cl2N5O5S
CAS No.	862189-96-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (165.40 mM)

References and Literature

1. Paick, J.S., et al., Efficacy and safety of mirodenafil, a new oral phosphodiesterase type 5 inhibitor, for treatment of erectile dysfunction. J Sex Med, 2008. 5(11): p. 2672-80. 2. Kim, B.H., et al., Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: a single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea. Clin Ther, 2009. 31(6): p. 1234-43.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Inhibitor Library Bioactive Compounds Library Max Metabolism Compound Library NO PAINS Compound Library Approved Drug Library FDA-Approved & Pharmacopeia Drug Library Clinical Compound Library Bioactive Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Keywords

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