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Molsidomine

Catalog No. T0109   CAS 25717-80-0
Synonyms: Morsydomine, SIN-10, Corvaton

Molsidomine (Corvaton) is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO) upon decay as the actual vasodilating compound.

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Molsidomine Chemical Structure
Molsidomine, CAS 25717-80-0
Pack Size Availability Price/USD Quantity
200 mg In stock $ 32.00
1 mL * 10 mM (in DMSO) In stock $ 50.00
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Purity: 100%
Purity: 99.96%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Molsidomine (Corvaton) is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO) upon decay as the actual vasodilating compound.
In vivo Molsidomine (50, 100, 250 μg/kg) reduces coronary flow while the coronary resistance remains unaffected by molsidomine. Molsidomine decreases myocardial oxygen consumption. Heart rate and contractility remains unchanged by molsidomine. Stroke volume and cardiac output fall after molsidomine. The fall in blood pressure after molsidomine follows the reduction in cardiac output as sequel of lowered preload and venous return to the heart[1].
Synonyms Morsydomine, SIN-10, Corvaton
Molecular Weight 242.23
Formula C9H14N4O4
CAS No. 25717-80-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45 mg/mL (185.8 mM)

H2O: 9 mg/mL (37.15 mM)

Ethanol: 21 mg/mL(86.7 mM)

TargetMolReferences and Literature

1. Volker B. Fiedler, et al. Naunyn-Schmiedeberg's Archives of Pharmacology. 1981, 317(1):71-77.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Approved Drug Library Anti-Cancer Drug Library Immunology/Inflammation Compound Library Pyroptosis Compound Library NO PAINS Compound Library Anti-Cancer Compound Library Drug-Fragment Library Anti-Liver Cancer Compound Library Approved Drug Library Anti-Breast Cancer Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Molsidomine 25717-80-0 Immunology/Inflammation NF-Κb NOD inhibit Drug Metabolite Morsydomine SIN-10 SIN10 Inhibitor Corvaton SIN 10 inhibitor

 

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