Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Molsidomine (Corvaton) is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO) upon decay as the actual vasodilating compound.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
200 mg | In stock | $ 32.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Molsidomine (Corvaton) is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO) upon decay as the actual vasodilating compound. |
In vivo | Molsidomine (50, 100, 250 μg/kg) reduces coronary flow while the coronary resistance remains unaffected by molsidomine. Molsidomine decreases myocardial oxygen consumption. Heart rate and contractility remains unchanged by molsidomine. Stroke volume and cardiac output fall after molsidomine. The fall in blood pressure after molsidomine follows the reduction in cardiac output as sequel of lowered preload and venous return to the heart[1]. |
Synonyms | Morsydomine, SIN-10, Corvaton |
Molecular Weight | 242.23 |
Formula | C9H14N4O4 |
CAS No. | 25717-80-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (185.8 mM)
H2O: 9 mg/mL (37.15 mM)
Ethanol: 21 mg/mL(86.7 mM)
You can also refer to dose conversion for different animals. More
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Molsidomine 25717-80-0 Immunology/Inflammation NF-Κb NOD inhibit Drug Metabolite Morsydomine SIN-10 SIN10 Inhibitor Corvaton SIN 10 inhibitor