Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Moracin M, a phenolic compound found in the skin of Morus alba Linn., effectively inhibits phosphodiesterase-4 (PDE4), exhibiting IC50 values of 2.9 μM and 4.5 μM for PDE4D2 and PDE4B2, respectively, and showing significantly lesser activity on PDE5A1 and PDE9A2 with values over 40 μM and 100 μM, respectively. This compound demonstrates notable anti-inflammatory activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
5 mg | In stock | $ 79.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 220.00 | |
50 mg | In stock | $ 328.00 | |
100 mg | In stock | $ 493.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 83.00 |
Description | Moracin M, a phenolic compound found in the skin of Morus alba Linn., effectively inhibits phosphodiesterase-4 (PDE4), exhibiting IC50 values of 2.9 μM and 4.5 μM for PDE4D2 and PDE4B2, respectively, and showing significantly lesser activity on PDE5A1 and PDE9A2 with values over 40 μM and 100 μM, respectively. This compound demonstrates notable anti-inflammatory activity. |
Targets&IC50 | PDE5A1:>40 μM (IC50), PDE9A2:>100 μM (IC50), PDE4D2:2.9 μM (IC50), PDE4B2:4.5 μM (IC50) |
Molecular Weight | 242.23 |
Formula | C14H10O4 |
CAS No. | 56317-21-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 15.3 mg/mL (63.2 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Moracin M 56317-21-6 Metabolism PDE inhibitor inhibit