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NG-Nitroarginine methyl ester

Catalog No. T25865 CAS 50903-99-6

Synonyms: ω-Nitroarginine methyl, L-NAME

NG-Nitroarginine methyl ester (ω-Nitroarginine methyl) is a non-selective nitric oxide synthase inhibitor. It has been utilized experimentally to induce hypertension.

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NG-Nitroarginine methyl ester Chemical Structure

NG-Nitroarginine methyl ester, CAS 50903-99-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 148.00
5 mg	In stock	$ 336.00
10 mg	In stock	$ 497.00
25 mg	In stock	$ 793.00
50 mg	In stock	$ 1,130.00
100 mg	In stock	$ 1,520.00
500 mg	In stock	$ 2,970.00
1 mL * 10 mM (in DMSO)	In stock	$ 298.00

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Purity: 99.72%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

NG-Nitroarginine methyl ester (ω-Nitroarginine methyl) is a non-selective nitric oxide synthase inhibitor. It has been utilized experimentally to induce hypertension.

Synonyms	ω-Nitroarginine methyl, L-NAME
Molecular Weight	233.23
Formula	C7H15N5O4
CAS No.	50903-99-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 2.33 mg/ml (10 mM)

References and Literature

1. Güney HZ, Görgün CZ, Tunçtan B, Uludağ O, Hodoğlugil U, Abacioğlu N, Zengil H. Circadian-rhythm-dependent effects of L-NG-nitroarginine methyl ester (L-NAME) on morphine-induced analgesia. Chronobiol Int. 1998 May;15(3):283-9. 2. Tsuda K. Letter by Tsuda regarding article, "Plasminogen activator inhibitor-1 antagonist TM5441 attenuates Nω-nitro-L-arginine methyl ester-induced hypertension and vascular senescence". Circulation. 2014 Aug 26;130(9):e83. 3. Bulbul T, Akosman MS, Yilmaz O, Ulutas E, Bulbul A. Supplementary dietary nitric oxide donor (sodium nitroprusside) or inhibitor (NG-nitro-L-arginine methyl ester) depressed growth performance and ovarian primordial and primary follicles in Japanese quail (Coturnix coturnix japonica) in a dose-dependent manner. Br Poult Sci. 2015;56(1):113-20. 4. Shimizu M, Kochi T, Shirakami Y, Genovese S, Epifano F, Fiorito S, Mori T, Tanaka T, Moriwaki H. A newly synthesized compound, 4'-geranyloxyferulic acid-N(omega)-nitro-L-arginine methyl ester suppresses inflammation-associated colorectal carcinogenesis in male mice. Int J Cancer. 2014 Aug 15;135(4):774-84.

Citations

1. Ke F, Kuang W, Hu X, et al.A novel vaccine targeting β1-adrenergic receptor.Hypertension Research.2023: 1-14.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Drug Repurposing Compound Library Immunology/Inflammation Compound Library Bioactive Compound Library Bioactive Compounds Library Max Anti-Hypertension Compound Library Clinical Compound Library Anti-Cardiovascular Disease Compound Library

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Keywords

NG-Nitroarginine methyl ester 50903-99-6 Immunology/Inflammation NO Synthase w-Nitroarginine methyl ω-Nitroarginine methyl NGNitroarginine methyl ester L-NAME omega-Nitroarginine methyl NG Nitroarginine methyl ester inhibitor inhibit

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