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NPC 567 acetate

Catalog No. T21060L CAS T21060L

Synonyms: NPC 567 acetate(109333-26-8 Free base)

NPC 567 acetate is a bradykinin B2 antagonist and can be used in studies about the treatment of allergic airway disease.

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NPC 567 acetate, CAS T21060L

Pack Size	Availability	Price/USD
1 mg	In stock	$ 195.00
5 mg	In stock	$ 437.00
10 mg	In stock	$ 646.00
25 mg	In stock	$ 987.00
50 mg	In stock	$ 1,380.00
100 mg	In stock	$ 1,860.00

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Purity: 97.72%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

NPC 567 acetate is a bradykinin B2 antagonist and can be used in studies about the treatment of allergic airway disease.

In vivo

In the NPC 567 acetate (2.5 mg) -treated pigs, the resistance only increased from 2.9 cm H2O/l/s to 6.5 cm H2O/l/s. There was also a higher reduction in dynamic lung compliance in the controls than in the treated animals upon allergen challenge. The histamine concentration in urine in the control pigs was markedly elevated after allergen challenge peaking at 15-30 min. This release was inhibited in the NPC 567 acetate-treated pigs[1].

Synonyms	NPC 567 acetate(109333-26-8 Free base)
Molecular Weight	1342.5
Formula	C62H91N19O15
CAS No.	T21060L

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Sylvin H, et al. The effect of a bradykinin B2 receptor antagonist, NPC-567, on allergen-induced airway responses in a porcine model. Inflamm Res. 2001 Sep;50(9):453-9. 2. Abraham WM. The potential role of bradykinin antagonists in the treatment of asthma. Agents Actions Suppl. 1992;38 ( Pt 3):439-49.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Bioactive Compound Library Peptide Compound Library Bioactive Compounds Library Max

Related Products

Related compounds with same targets

ELN-441958 B-Raf IN 14 R715 TFA(185052-09-9 free base) (Hyp³)-Bradykinin acetate Bradykinin Lys-(Des-Arg9,Leu8)-Bradykinin Anatibant 2HCl Des-Arg9-[Leu8]-Bradykinin acetate

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

NPC 567 acetate T21060L GPCR/G Protein Bradykinin Receptor NPC-567 Acetate NPC 567 acetate(109333-26-8 Free base) NPC567 Acetate NPC 567 Acetate inhibitor inhibit

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