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NS1643

Catalog No. T3192 CAS 448895-37-2

Purity 99.00% Datasheet MSDS

NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.

NS1643, CAS 448895-37-2

Pack Size	Availability	Price/USD
10 mg	In stock	63.00
25 mg	In stock	112.00
50 mg	In stock	203.00
100 mg	In stock	347.00
200 mg	Inquiry	451.00
500 mg	Inquiry	950.00
1 mL * 10 mM (in DMSO)	In stock	69.00

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Purity 99.00%

HNMR COA Datasheet MSDS

Purity 98.37%

HNMR HPLC COA Datasheet MSDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description	NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.
Targets&IC50	hERG,

Molecular Weight	380.24
Formula	C15H10F6N2O3
CAS No.	448895-37-2

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

Ethanol: 100 mM

DMSO: 25 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Casis O, et al. Mol Pharmacol. 2006 Feb;69(2):658-65. 2. Sun XJ, et al. The Role of Histone Acetyltransferases in Normal and Malignant Hematopoiesis. Front Oncol. 2015 May 26;5:108.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library Inhibitor Library Anti-cancer Compound Library Autophagy Compound Library Ion Channel Inhibitor Library Tyrosine kinase inhibitor library Fluorochemical Library Angiogenesis related Compound Library JAK STAT Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.