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Niraparib tosylate monohyrate

Catalog No. T9497 CAS 1613220-15-7

Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base-excision repair (BER) pathway.

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Niraparib tosylate monohyrate Chemical Structure

Niraparib tosylate monohyrate, CAS 1613220-15-7

Pack Size	Availability	Price/USD
5 mg	In stock	$ 55.00
10 mg	In stock	$ 79.00
25 mg	In stock	$ 119.00
50 mg	In stock	$ 147.00
100 mg	In stock	$ 228.00
200 mg	In stock	$ 343.00
500 mg	In stock	$ 573.00
1 mL * 10 mM (in DMSO)	In stock	$ 70.00

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Purity: 99.09%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	510.61
Formula	C26H30N4O5S
CAS No.	1613220-15-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 1 mg/mL, Sonication is recommended.

DMSO: 70 mg/mL (142.11 mM)

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Drug Library EMA Approved Drug Library Inhibitor Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Active Compound Library DNA Damage & Repair Compound Library Anti-Prostate Cancer Compound Library Epigenetics Compound Library FDA-Approved & Pharmacopeia Drug Library

Related Products

Related compounds with same targets

Rucaparib monocamsylate PARP-1/2-IN-2 YCH1899 GeA-69 PARP1-IN-15 A-966492 Sageone Effusanin E

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

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