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Nitidine chloride

Catalog No. T5S0761   CAS 13063-04-2
Synonyms: Nitidine chloride, NF-κB, PTK2, inhibit, Apoptosis, ERK, Inhibitor, FAK, Parasite, PTK2 protein tyrosine kinase 2, Topoisomerase, Nuclear factor-kappaB, Nuclear factor-κB, Focal adhesion kinase, Extracellular signal regulated kinases, p38 MAPK, Nitidine, STAT

1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and identifies efficacy in vivo in a mouse model of HCC.

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Nitidine chloride, CAS 13063-04-2
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Purity: 98%
Biological Description
Chemical Properties
Storage & Solubility Information
Description 1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and identifies efficacy in vivo in a mouse model of HCC.
Synonyms Nitidine chloride, NF-κB, PTK2, inhibit, Apoptosis, ERK, Inhibitor, FAK, Parasite, PTK2 protein tyrosine kinase 2, Topoisomerase, Nuclear factor-kappaB, Nuclear factor-κB, Focal adhesion kinase, Extracellular signal regulated kinases, p38 MAPK, Nitidine, STAT
Molecular Weight 383.83
Formula C21H18ClNO4
CAS No. 13063-04-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

DMSO: 10 mg/mL(26.1 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Wang Z , Jiang W , Zhang Z , et al. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kappaB pathway in RAW 264.7 cells[J]. Journal of ethnopharmacology, 2012, 144(1).

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Compound Library HIF-1 Signaling Pathway Compound Library Traditional Chinese Medicine Monomer Library Anti-Gastroenteritis Natural Product Library Natural Product Library for HTS Anti-Tumor Natural Product Library DNA Damage & Repair Compound Library Immunology/Inflammation Compound Library Alkaloid Natural Product Library Anti-Cancer Active Compound Library

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Related compounds with same targets
Salinomycin sodium salt (S)-(−)-Perillyl alcohol CPI-360 Chetomin WYE-132 GSK1904529A LYN-1604 Curzerene

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.