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Nitidine chloride

Catalog No. T5S0761 CAS 13063-04-2

Synonyms: Nitidine chloride, NF-κB, PTK2, inhibit, Apoptosis, ERK, Inhibitor, FAK, Parasite, PTK2 protein tyrosine kinase 2, Topoisomerase, Nuclear factor-kappaB, Nuclear factor-κB, Focal adhesion kinase, Extracellular signal regulated kinases, p38 MAPK, Nitidine, STAT

1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and identifies efficacy in vivo in a mouse model of HCC.

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Nitidine chloride, CAS 13063-04-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Nitidine chloride, NF-κB, PTK2, inhibit, Apoptosis, ERK, Inhibitor, FAK, Parasite, PTK2 protein tyrosine kinase 2, Topoisomerase, Nuclear factor-kappaB, Nuclear factor-κB, Focal adhesion kinase, Extracellular signal regulated kinases, p38 MAPK, Nitidine, STAT
Molecular Weight	383.83
Formula	C21H18ClNO4
CAS No.	13063-04-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

DMSO: 10 mg/mL(26.1 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Wang Z , Jiang W , Zhang Z , et al. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kappaB pathway in RAW 264.7 cells[J]. Journal of ethnopharmacology, 2012, 144(1).

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library HIF-1 Signaling Pathway Compound Library Traditional Chinese Medicine Monomer Library Anti-Gastroenteritis Natural Product Library Natural Product Library for HTS Anti-Tumor Natural Product Library DNA Damage & Repair Compound Library Immunology/Inflammation Compound Library Alkaloid Natural Product Library Anti-Cancer Active Compound Library

Related Products

Related compounds with same targets

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.