Powder: -20°C for 3 years | In solvent: -80°C for 1 year
OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 35.00 | |
2 mg | In stock | $ 50.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 132.00 | |
25 mg | In stock | $ 273.00 | |
50 mg | In stock | $ 526.00 | |
100 mg | In stock | $ 731.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 72.00 |
Description | OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain. |
Targets&IC50 | BRPF1B:100 nM(Kd), BRPF2:500 nM(Kd) |
In vitro | As a chemical probe for BRPF bromodomains, OF-1 increases thermal stability in the cellular thermal shift assay of full length BRPF1B at 1 μM and also demonstrates accelerated FRAP recovery at 5 μM in the BRPF2 FRAP assay. In addition, OF-1 shows modest general cytotoxicity. [1] |
Molecular Weight | 440.31 |
Formula | C17H18BrN3O4S |
CAS No. | 919973-83-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8.8 mg/mL (20 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
OF-1 919973-83-4 Chromatin/Epigenetic Epigenetic Reader Domain Inhibitor inhibit OF1 OF 1 inhibitor