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Octopamine hydrochloride

Catalog No. T0469   CAS 770-05-8
Synonyms: (±)-p-Octopamine hydrochlorid, (+,-)-Octopamine HCl

Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) is a biogenic monoamine structurally associated with noradrenaline. It can serve as a neurohormone, a neurotransmitter, and a neuromodulator in invertebrates.

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Octopamine hydrochloride Chemical Structure
Octopamine hydrochloride, CAS 770-05-8
Pack Size Availability Price/USD Quantity
500 mg In stock $ 45.00
1 g In stock $ 53.00
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Purity: 99.89%
Purity: 99.85%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) is a biogenic monoamine structurally associated with noradrenaline. It can serve as a neurohormone, a neurotransmitter, and a neuromodulator in invertebrates.
In vitro Octopamine is present in relatively high concentrations in neuronal as well as in non-neuronal tissues of most invertebrate species studied, and modulates almost every physiological process. Octopamine acts as neurohormone including desensitization of sensory inputs, influence on learning and memory, or regulation of the mood of the animal in the central nervous system. Octopamine is the only neuroactive non-peptide transmitter whose physiological role is restricted to invertebrates, and all octopamine receptors belong to the family of G-protein coupled receptors. [1]
In vivo Octopamine (10 mg/mL) is necessary for the acquisition of sugar memory in Drosophila. [2] Octopamine treatment increases responsiveness to brood pheromone and decreased responsiveness to social inhibition. Octopamine acts as an important source of variation in response thresholds and as a modulator of pheromonal communication in insect societies. [3] Octopamine (10 μM) injected into the mushroom body (MB) calyces or the antennal lobe but not the lateral protocerebral lobe produces a lasting, pairing-specific enhancement of extension of the proboscis. Octopamine (10 μM) injected into the MB calyces results in an additional pairing-specific effect, because it does not lead to an acquisition but a consolidation after conditioning. [4] Octopamine treatment significantly elevates levels of octopamine in the brain and caused a significant dose-dependent increase in the number of new foragers. Octopamine treatment is effective only when given to bees old enough to forage, i.e., older than 4 days of age. Octopamine influences division of labor in honey bee colonies. [5]
Synonyms (±)-p-Octopamine hydrochlorid, (+,-)-Octopamine HCl
Molecular Weight 189.639
Formula C8H12ClNO2
CAS No. 770-05-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 200.4 mM

H2O: 200.4 mM

TargetMolReferences and Literature

1. Roeder T, et al. Prog Neurobiol, 1999, 59(5), 533-561. 2. Schwaerzel M, et al. J Neurosci, 2003, 23(33), 10495-10502. 3. Barron AB, et al. J Comp Physiol A Neuroethol Sens Neural Behav Physiol, 2002, 188(8), 603-10. 4. Hammer M, et al. Learn Mem, 1998, 5(1-2), 146-156. 5. Schulz DJ, et al. J Comp Physiol A, 2001, 187(1), 53-61.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Approved Drug Library Anti-Cancer Drug Library Anti-Neurodegenerative Disease Compound Library Drug Repurposing Compound Library Anti-Cardiovascular Disease Compound Library Human Endogenous Metabolite Compound Library Plus Anti-Parkinson's Disease Compound Library Human Metabolite Library Adrenergic Receptor-Targeted Compound Library FDA-Approved & Pharmacopeia Drug Library

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Keywords

Octopamine hydrochloride 770-05-8 GPCR/G Protein Metabolism Neuroscience Dopamine Receptor Adrenergic Receptor Endogenous Metabolite neurotransmitter Inhibitor p-Octopamine hydrochlorid memory inhibit invertebrates learning (±)-p-Octopamine hydrochlorid neurohormone (+,-)-Octopamine HCl Octopamine Hydrochloride neuromodulator Octopamine Beta Receptor Octopamine HCl inhibitor

 

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