Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 43.00 | |
50 mg | In stock | Inquiry | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors. |
In vitro | Oxotremorine M iodide robustly elicits a phosphoinositide response (EC50 = 0.22 μM). Oxotremorine M iodide shows EC50s of 0.36, 0.52, 1.62, and 1.48 μM for wild-type, M2, M3, and M2/M3 knockout mice, respectively[1]. Oxotremorine M iodide (0.1-30 μM) dose-dependently inhibits KCNQ2/3 currents[2]. |
In vivo | In male Sprague-Dawley albino rats, Oxotremorine M iodide (0.5 mg/kg; s.c.) increases DA release in the medial prefrontal cortex without affecting the nucleus accumbens[4]. |
Synonyms | Oxotremorine methiodide |
Molecular Weight | 322.19 |
Formula | C11H19IN2O |
CAS No. | 3854-04-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (310.4 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Oxotremorine M iodide 3854-04-4 Neuroscience AChR Oxotremorine M Iodide Oxotremorine methiodide inhibitor inhibit