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Oxysophoridine

Catalog No. T2S1008   CAS 54809-74-4
Synonyms: Sophoridine N-oxide

Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, that the effect may be due to its ability to inhibit oxidative stress and expression of the N-methyl-D-aspartate receptor subunit NR1.Oxysophoridine ameliorates cardiac damage in a rat model of AMI and that this cardioprotection may be linked with its anti-oxidative, anti-apoptotic and anti-inflammatory properties.

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Oxysophoridine Chemical Structure
Oxysophoridine, CAS 54809-74-4
Pack Size Availability Price/USD Quantity
20 mg In stock $ 60.00
1 mL * 10 mM (in DMSO) In stock $ 50.00
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Purity: 100%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, that the effect may be due to its ability to inhibit oxidative stress and expression of the N-methyl-D-aspartate receptor subunit NR1.Oxysophoridine ameliorates cardiac damage in a rat model of AMI and that this cardioprotection may be linked with its anti-oxidative, anti-apoptotic and anti-inflammatory properties.
Source
Synonyms Sophoridine N-oxide
Molecular Weight 264.36
Formula C15H24N2O2
CAS No. 54809-74-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (94.56 mM)

TargetMolReferences and Literature

1. Rui C , Yuxiang L , Ning J , et al. Anti-apoptotic and Neuroprotective Effects of Oxysophoridine on Cerebral Ischemia Both In Vivo and In Vitro[J]. Planta Medica, 2013, 79(11):916-923. 2. Cong, Meng, Chuan, et al. Oxysophoridine attenuates the injury caused by acute myocardial infarction in rats through anti-oxidative, anti-inflammatory and anti-apoptotic pathways.[J]. Molecular Medicine Reports, 2015. 3. Wang T F , Lei Z , Li Y X , et al. Oxysophoridine Protects Against Focal Cerebral Ischemic Injury by Inhibiting Oxidative Stress and Apoptosis in Mice[J]. Neurochemical Research, 2013, 38(11):2408-2417.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Aging Compound Library Traditional Chinese Medicine Monomer Library Natural Product Library NO PAINS Compound Library Immunology/Inflammation Compound Library Ferroptosis Compound Library Drug-induced Liver Injury (DILI) Compound Library Antioxidant Compound Library Bioactive Compounds Library Max Oxidation-Reduction Compound Library

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Keywords

Oxysophoridine 54809-74-4 Apoptosis oxidation-reduction Antioxidant Sophoridine N-oxide Inhibitor inhibit inhibitor

 

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