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PEAQX

Catalog No. T4171   CAS 459836-30-7
Synonyms: NVP-AAM077

PEAQX (NVP-AAM077)(NVP-AAM 077) is an effective and orally available NMDA antagonist. It can inhibit human NMDA receptors for 1A/2A(IC50: 270 nM), rather than 1A/2B(29, 600 nM).

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PEAQX Chemical Structure
PEAQX, CAS 459836-30-7
Pack Size Availability Price/USD Quantity
1 mg In stock $ 46.00
2 mg In stock $ 64.00
5 mg In stock $ 117.00
10 mg In stock $ 211.00
25 mg In stock $ 380.00
50 mg In stock $ 591.00
100 mg In stock $ 843.00
1 mL * 10 mM (in DMSO) In stock $ 167.00
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Purity: 100%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description PEAQX (NVP-AAM077)(NVP-AAM 077) is an effective and orally available NMDA antagonist. It can inhibit human NMDA receptors for 1A/2A(IC50: 270 nM), rather than 1A/2B(29, 600 nM).
Targets&IC50 PEAQX(NVP-AAM 077) is an effective and orally available human NMDA receptors for 1A/2A:270 nM
Synonyms NVP-AAM077
Molecular Weight 454.21
Formula C17H17BrN3O5P
CAS No. 459836-30-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 6 mg/mL (13.21 mM)

TargetMolReferences and Literature

1. Auberson YP, et al. 5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. Bioorg Med Chem Lett. 2002 Apr 8;12(7):1099-102. 2. Anastasio NC, et al. Differential role of N-methyl-D-aspartate receptor subunits 2A and 2B in mediating phencyclidine-induced perinatal neuronal apoptosis and behavioral deficits. Neuroscience. 2009 Nov 10;163(4):1181-91.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Neurodegenerative Disease Compound Library Highly Selective Inhibitor Library Neuronal Signaling Compound Library Bioactive Compounds Library Max Antidepressant Compound Library Ion Channel Inhibitor Library Anti-Alzheimer's Disease Compound Library Inhibitor Library Bioactive Compound Library Anti-Parkinson's Disease Compound Library

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Keywords

PEAQX 459836-30-7 Membrane transporter/Ion channel Neuroscience NMDAR iGluR Inhibitor Ionotropic glutamate receptors inhibit NVP-AAM 077 NVP-AAM077 NVP-AAM-077 inhibitor

 

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