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PI-3065

Catalog No. T2083   CAS 955977-50-1
Synonyms: PI3065

PI-3065 is a novel potent and selective PI3K p110δ inhibitor.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
PI-3065 Chemical Structure
PI-3065, CAS 955977-50-1
Pack Size Availability Price/USD Quantity
1 mg In stock $ 41.00
2 mg In stock $ 59.00
5 mg In stock $ 97.00
10 mg In stock $ 147.00
25 mg In stock $ 267.00
50 mg In stock $ 447.00
100 mg In stock $ 637.00
500 mg In stock $ 1,330.00
1 mL * 10 mM (in DMSO) In stock $ 109.00
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Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description PI-3065 is a novel potent and selective PI3K p110δ inhibitor.
Targets&IC50 p110δ:15 nM, p110β:1078 nM
In vitro PI-3065 shows no inhibition on the growth of 4T1 cells, which do not expressing detectable levels of p110δ. [1]
Cell Research Proliferation of 4T1 cells is assayed following a 4-h treatment with the indicated p110δ inhibitors, then washing and MTS staining are carried out after 48 h culture. (Only for Reference)
Synonyms PI3065
Molecular Weight 506.64
Formula C27H31FN6OS
CAS No. 955977-50-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10.1 mg/mL (20 mM)

TargetMolReferences and Literature

1. Ali K, et al. Nature. 2014, 510(7505), 407-411.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Prostate Cancer Compound Library Anti-Obesity Compound Library Anti-Cancer Metabolism Compound Library PI3K-AKT-mTOR Compound Library Anti-Pancreatic Cancer Compound Library Pyroptosis Compound Library Inhibitor Library DNA Damage & Repair Compound Library Stem Cell Differentiation Compound Library Target-Focused Phenotypic Screening Library

Related Products

Related compounds with same targets
KU-55933 (R)-(-)-Rolipram STL127705 KU-0060648 PIK-90 Pictilisib dimethanesulfonate KU-57788 PI3K-IN-1

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

PI-3065 955977-50-1 DNA Damage/DNA Repair PI3K/Akt/mTOR signaling DNA-PK PI3K mTOR inhibit PI3065 PI 3065 Inhibitor Phosphoinositide 3-kinase inhibitor

 

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