Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PI3Kδ-IN-1 is an efficacious PI3Kδ inhibitor (IC50 of 1.7 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 98.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 397.00 | |
25 mg | In stock | $ 663.00 | |
50 mg | In stock | $ 945.00 | |
100 mg | In stock | $ 1,280.00 |
Description | PI3Kδ-IN-1 is an efficacious PI3Kδ inhibitor (IC50 of 1.7 nM). |
Targets&IC50 | PI3Kδ:1.7 nM |
In vitro | PI3Kδ-IN-1 has an improved human/rodent in vitro stability correlation and a good permeability profile[1]. |
In vivo | PI3Kδ-IN-1 shows greater than 50% suppression of paw swelling in mice. PI3Kδ-IN-1 has an EC50 of 10 nM at 24 h (ED50 of ∼1.25 mg/kg) in mice[1]. |
Molecular Weight | 471.44 |
Formula | C22H20F3N7O2 |
CAS No. | 1911564-39-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 18.0 mg/mL (37.6 mM), Sonification and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PI3Kδ-IN-1 1911564-39-0 PI3K/Akt/mTOR signaling PI3K PI3Kδ IN 1 PI-3Kδ-IN-1 PI3Kdelta-IN-1 PI3KδIN1 inhibitor inhibit