Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PPTN is a high-affinity, competitive and highly selective antagonist of P2Y14 receptor(KB value of 434 pM), with anti-inflammatory and immune activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 449.00 | |
10 mg | In stock | $ 659.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,390.00 | |
100 mg | In stock | $ 1,880.00 | |
500 mg | In stock | $ 3,780.00 |
Description | PPTN is a high-affinity, competitive and highly selective antagonist of P2Y14 receptor(KB value of 434 pM), with anti-inflammatory and immune activity. |
Targets&IC50 | P2Y14 receptor:434 pM (KB) |
In vitro | PPTN exhibits strong selectivity for the P2Y14-R over the other seven nucleotide-activated P2Y receptors. PPTN inhibits UDP-glucose-promoted chemotaxis in differentiated HL-60 human promyelocytic leukemia cells with IC50s of ~1 nM in the presence of 10 μM UDP-glucose and ~4 nM in the presence of 100 μM[1]. |
Molecular Weight | 475.5 |
Formula | C29H24F3NO2 |
CAS No. | 1160271-30-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Insoluble
You can also refer to dose conversion for different animals. More
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PPTN 1160271-30-6 GPCR/G Protein Neuroscience P2Y Receptor inhibitor inhibit