Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, specifically compound LP2. PAC serves as the linker for ADCs and PROTACs that are conjugated to an antibody. Notably, when PAC is conjugated to an antibody, it exhibits enhanced degradation of estrogen receptor-alpha (ERα) compared to PROTAC alone [1].
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Description | PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, specifically compound LP2. PAC serves as the linker for ADCs and PROTACs that are conjugated to an antibody. Notably, when PAC is conjugated to an antibody, it exhibits enhanced degradation of estrogen receptor-alpha (ERα) compared to PROTAC alone [1]. |
Molecular Weight | 1220.434 |
Formula | C71H77N7O12 |
CAS No. | 2158322-29-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PROTAC ER Degrader-3 2158322-29-1 Others PROTAC ER Degrader3 PROTAC ER Degrader 3 inhibitor inhibit