Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with μM-range affinity. PROTAC Mcl1 degrader-1, a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl-1 inhibitor with an IC50 of 0.78 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | $ 456.00 | |
5 mg | Inquiry | $ 813.00 | |
10 mg | Inquiry | $ 1,240.00 | |
50 mg | Inquiry | Inquiry | |
100 mg | Inquiry | Inquiry |
Description | PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with μM-range affinity. PROTAC Mcl1 degrader-1, a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl-1 inhibitor with an IC50 of 0.78 μM. |
Targets&IC50 | MCL1:0.78 μM |
Molecular Weight | 909.84 |
Formula | C45H45BrN6O8S |
CAS No. | 2163793-38-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (54.95 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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PROTAC Mcl1 degrader-1 2163793-38-0 Apoptosis BCL PROTAC Mcl-1 degrader-1 PROTAC Mcl1 degrader 1 PROTAC Mcl1 degrader1 inhibitor inhibit