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PSB 1115

Catalog No. T23201 CAS 152529-79-8

PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.

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PSB 1115, CAS 152529-79-8

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.
In vitro	PSB 1115 reversed the decrease in plasma insulin induced by NECA[1].
In vivo	The effect of PSB 1115 was obvious in diabetic GotoKakizaki rats: plasma insulin was increased whereas blood glucose was unchanged. The adenosine levels were not different in normal Wistar rats and in diabetic GotoKakzaki rats[1].

Molecular Weight	350.35
Formula	C14H14N4O5S
CAS No.	152529-79-8

Storage

store at low temperature

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: <38.84mg/mL

H2O: <7.77mg/ml

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Rüsing D, et al. The impact of adenosine and A(2B) receptors on glucose homoeostasis. J Pharm Pharmacol. 2006 Dec;58(12):1639-45.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

PSB 1115 152529-79-8 GPCR/G Protein Neuroscience Adenosine Receptor Inhibitor inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.