Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PhiKan 083 is a carbazole derivative
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 113.00 | |
25 mg | In stock | $ 247.00 | |
50 mg | In stock | $ 368.00 | |
100 mg | In stock | $ 543.00 | |
500 mg | In stock | $ 1,160.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 69.00 |
Description | PhiKan 083 is a carbazole derivative |
Targets&IC50 | p53-Y220C (Ln229 cells):150 μM(Kd) , p53-Y220C:167 μM(Kd) |
In vitro | PhiKan 083 reduces the cell viability of engineered variants of Ln229 cells, in conbination with NSC 123127 (1 μM) enhances the pro-apoptotic activity in all variants of Ln229 cells (p53wt, p53Y220C, p53G245S, p53R282W)[1]. |
Molecular Weight | 238.33 |
Formula | C16H18N2 |
CAS No. | 880813-36-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 100 mg/mL (419.59 mM), Sonification is recommended.
DMSO: 115 mg/mL (482.52 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PhiKan 083 880813-36-5 Apoptosis Mdm2 PhiKan-083 Inhibitor MDM-2/p53 PhiKan083 inhibit inhibitor