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Phytic acid

Catalog No. T2971 CAS 83-86-3

Synonyms: Inositol hexaphosphate, inositol hexakisphosphate, inositol polyphosphate, myo-Inositol, hexakis(dihydrogen phosphate), Fytic Acid

Phytic acid (Fytic Acid) is a complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.

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Phytic acid, CAS 83-86-3

Pack Size	Availability	Price/USD
5 mg	In stock	$ 40.00
10 mg	In stock	$ 55.00
25 mg	In stock	$ 87.00
50 mg	In stock	$ 126.00
100 mg	In stock	$ 183.00
500 mg	In stock	$ 453.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 99.31%

Biological Description

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Storage & Solubility Information

Description	Phytic acid (Fytic Acid) is a complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
In vitro	Phytic acid, a major phosphorus storage compound of most seeds and cereal grains, contributes about 1 to 7% of their dry weight. It may account for more than 70% of the total kernel phosphorus. Phytic acid has the strong ability to chelate multivalent metal ions, especially zinc, calcium, and iron. The binding can result in very insoluble salts that are poorly absorbed from the gastrointestinal tract, which results in poor bioavailability of minerals. Phytic acid is also considered to be a natural antioxidant and is suggested to have potential functions of reducing lipid peroxidation and as a preservative in foods[1]. Phytic acid inhibits the formation of uric acid from xanthine with an IC50 of about 30 mM. The generation of the superoxide is greatly affected by phytic acid; the IC50 is about 6 mM, indicating that the superoxide generating domain of XO is more sensitive to phytic acid[2]. There has been observed an inhibition of tumor growth and induction of cell differentiation in the presence of phytic acid in a few cancer cell lines including colon, nipple, breast, prostate, cervix, liver, pancreas, melanoma and glioblastoma[3].
In vivo	Phytic acid has a neuroprotective effect in MPTP-induced PD model and the neuroprotection is correlated with its anti-inflammatory effect which may be associated with suppression of pathways that involved in NF-κB and p-ERK. Phytic acid significantly inhibits MPTP-induced dopaminergic cell loss in the substantia nigra (SN). Moreover, using immunohistochemistry method and quantitative polymerase chain reaction (qPCR), microglial activation and inducible nitric oxide synthase (iNOS) are found to be markedly repressed by phytic acid[4].
Source	Natural Products > Poaceae > Oryza

Synonyms	Inositol hexaphosphate, inositol hexakisphosphate, inositol polyphosphate, myo-Inositol, hexakis(dihydrogen phosphate), Fytic Acid
Molecular Weight	660.04
Formula	C6H18O24P6
CAS No.	83-86-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (83.33 mM)

References and Literature

1. Zhou JR, et al. Phytic acid in health and disease. Crit Rev Food Sci Nutr. 1995 Nov;35(6):495-508. 2. Muraoka S, et al. Inhibition of xanthine oxidase by phytic acid and its antioxidative action. Life Sci. 2004 Feb 13;74(13):1691-700. 3. Nawrocka-Musial D, et al. Phytic acid--anticancer nutriceutic. Pol Merkur Lekarski. 2012 Jul;33(193):43-7. 4. Lv Y , Zhang Z , Hou L , et al. Phytic acid attenuates inflammatory responses and the levels of NF-κB and p-ERK in MPTP-induced Parkinson’s disease model of mice[J]. Neuroscience Letters, 2015, 597:132-136.

Related compound libraries

This product is contained In the following compound libraries：

Traditional Chinese Medicine Monomer Library Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library Inhibitor Library Anti-Cancer Active Compound Library Drug Repurposing Compound Library Human Endogenous Metabolite Compound Library Plus Human Metabolite Library Oxidation-Reduction Compound Library Preclinical Compound Library

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Related compounds with same targets

Fraxamoside Xanthine oxidase-IN-11 Benzbromarone Phytic acid dodecasodium salt hydrate Febuxostat URAT1&XO inhibitor 2 Baicalein Prudomestin

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Keywords

Phytic acid 83-86-3 Metabolism Endogenous Metabolite Xanthine Oxidase Inositol hexaphosphate inositol hexakisphosphate inositol polyphosphate Inositol Hexaphosphate myo-Inositol, hexakis(dihydrogen phosphate) Inhibitor Inositol inhibit Fytic Acid inhibitor

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