Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pregnenolone acetate is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. It acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. It can protect the brain from cannabis intoxication
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 50.00 | |
10 mg | In stock | $ 75.00 | |
25 mg | In stock | $ 128.00 | |
50 mg | In stock | $ 192.00 | |
100 mg | In stock | $ 287.00 | |
500 mg | In stock | $ 691.00 |
Description | Pregnenolone acetate is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. It acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. It can protect the brain from cannabis intoxication |
In vitro | Pregnenolone likely acts as a signaling-specific negative allosteric modulator binding to a site distinct from that occupied by orthosteric ligands. Pregnenolone does not modify agonist binding but only agonist efficacy[1]. |
In vivo | Pregnenolone acetate is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones.?It acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. It?can protect the brain from cannabis intoxication[1]. |
Synonyms | 3β-Hydroxy-5-pregnen-20-one acetate |
Molecular Weight | 358.51 |
Formula | C23H34O3 |
CAS No. | 1778-02-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Insoluble
H2O: Insoluble
You can also refer to dose conversion for different animals. More
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Pregnenolone acetate 1778-02-5 GPCR/G Protein Metabolism Endogenous Metabolite Cannabinoid Receptor 3beta-Hydroxy-5-pregnen-20-one Acetate 3b-Hydroxy-5-pregnen-20-one Acetate 3β-Hydroxy-5-pregnen-20-one Acetate Pregnenolone Acetate 3β-Hydroxy-5-pregnen-20-one acetate inhibitor inhibit