store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 33.00 | |
100 mg | In stock | $ 47.00 | |
200 mg | In stock | $ 68.00 | |
500 mg | In stock | $ 109.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 39.00 |
Description | Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle. |
Synonyms | Neopepulsan, Pro-Banthine, Neometantyl |
Molecular Weight | 448.4 |
Formula | C23H30BrNO3 |
CAS No. | 50-34-0 |
store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 198.5 mM
You can also refer to dose conversion for different animals. More
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Propantheline bromide 50-34-0 Neuroscience AChR Urination Propantheline Neopepulsan IBS Inhibitor mAChR Propantheline Bromide Muscarinic acetylcholine receptor cramps bladder Pro-Banthine Neometantyl bowel dysfunction inhibit inhibitor