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Pyrolin

Catalog No. TN4871 CAS 95-71-6

Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.

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Pyrolin, CAS 95-71-6

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500 mg	In stock	$ 42.00
1 mL * 10 mM (in DMSO)	In stock	$ 30.00

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Purity: 99.83%

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Description	Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.
In vitro	To explore the antifungal activity and potential mechanism of Pyrolin against Monilinia fructicola.METHODS AND RESULTS: Agar plate tests was conducted to test the inhibitory effect in-vitro and in vivo of Pyrolin.And doubling dilution method was used to determine the minimal inhibitory concentration(MIC) and minimal fugicide concentration(MFC).Polyphenol oxidase(PPO),peroxidase(POD) and phenylalanine ammonium-lyase(PAL) activities induced by inoculation with Pyrolin and M.fructicola were studied in peach.The ultrastructure of M.fructicola treated by Pyrolin was observed through scanning electron microscope(SEM) and transmission electron microscope(TEM). Pyrolin displayed strong antifungal activity to M.fructicola and the activity was significantly increased when the applied concentration was higher,the MIC value of 0.032 mg/mL and MFC value of 0.156 mg/mL.The activities of PPO,POD and PAL in peach increased significantly when inoculated with Pyrolin and M.fructicola,and maintained at a high level throughout the experiment.The observations with SEM revealed that the hyphae distorted,the adhesions mycelium occurred,the cell wall was rupture,cell surface occurred substance of flocculent agglutination.The observations with TEM showed that the hypha became thinning obviously,the inner structure confused,the hyphal cell was damaged severely.CONCLUSIONS: Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.
Source	Natural Products > Ericaceae > Pyrola

Molecular Weight	124.14
Formula	C7H8O2
CAS No.	95-71-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/ml (483.33 mM)

References and Literature

1. Inhibitory Effect and Antimicrobial Mechanism of Pyrolin on Monilinia fructicola in Peach. Scientia Agricultura Sinica, 2009,42 (8) :2784-2792.

Related compound libraries

This product is contained In the following compound libraries：

Tobacco Monomer Library Chinese Pharmacopoeia Natural Product Library Traditional Chinese Medicine Monomer Library Anti-infective Natural Product Library Anti-Infection Compound Library Bioactive Compound Library NO PAINS Compound Library Natural Product Library for HTS Bioactive Compounds Library Max Anti-Fungal Compound Library

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Keywords

Pyrolin 95-71-6 Microbiology/Virology Anti-infection inhibitor inhibit

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