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QX-314 chloride

Catalog No. T12608 CAS 5369-03-9

Purity 98.00% Datasheet

QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.

QX-314 chloride, CAS 5369-03-9

Pack Size	Availability	Price/USD
5 mg	inquiry	86.00
10 mg	inquiry	140.00
1 mL * 10 mM (in DMSO)	Inquiry	58.00

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Purity 98.00%

Datasheet MSDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description	QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.
Targets&IC50	sodium channel,

Appearance	solid
Molecular Weight	298.85
Formula	C16H27ClN2O
CAS No.	5369-03-9

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 14.29 mg/mL (47.82 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Rivera-Acevedo RE, et al. The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro. Anesthesiology. 2011 Jun;114(6):1425-34. 2. Talbot MJ, et al. Intracellular QX-314 inhibits calcium currents in hippocampal CA1 pyramidal neurons. J Neurophysiol. 1996 Sep;76(3):2120-4.

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