Powder: -20°C for 3 years | In solvent: -80°C for 1 year
QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 48.00 | |
50 mg | In stock | $ 82.00 | |
100 mg | In stock | $ 132.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 54.00 |
Description | QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel. |
In vitro | QX-314 chloride (1–60 mM) directly activates TRPV1 in a concentration-dependent manner.QX-314 chloride exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels (TRPV1) in vitro. QX-314 chloride (10 mM) inhibits calcium currents in hippocampal CA1 pyramidal neurons intracellular, and the low-threshold (T-type) Ca2+ currents are on average < 45% of control amplitude[2]. |
Molecular Weight | 298.85 |
Formula | C16H27ClN2O |
CAS No. | 5369-03-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 14.29 mg/mL (47.82 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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QX-314 chloride 5369-03-9 Membrane transporter/Ion channel Sodium Channel Inhibitor calcium QX314 chloride channel QX 314 Chloride Na channels QX314 sodium Na+ channels QX-314 QX314 Chloride inhibit QX 314 chloride QX 314 QX-314 Chloride inhibitor