Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antagonist activity at serotonin and dopamine receptors. Specifically, the D1 and D2 dopamine, the α1 adrenoreceptor and α2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also can inhibit the histamine H1 receptor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 50.00 | |
50 mg | In stock | $ 90.00 | |
100 mg | In stock | $ 117.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antagonist activity at serotonin and dopamine receptors. Specifically, the D1 and D2 dopamine, the α1 adrenoreceptor and α2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also can inhibit the histamine H1 receptor. |
Synonyms | ICI204636, Quetiapin |
Molecular Weight | 383.51 |
Formula | C21H25N3O2S |
CAS No. | 111974-69-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 36 mg/mL
You can also refer to dose conversion for different animals. More
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Quetiapine 111974-69-7 GPCR/G Protein Immunology/Inflammation Neuroscience AChR Adrenergic Receptor Dopamine Receptor 5-HT Receptor Histamine Receptor 5-HT2C 5-HT1A 5-hydroxytryptamine Receptor Antidepressant ICI204636 ICI 204636 anxiolytic inhibit Quetiapin Inhibitor Serotonin Receptor ICI-204636 5-HT2A inhibitor