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Ritodrine hydrochloride

Catalog No. T1433 CAS 23239-51-2

Synonyms: DU21220, Ritodrine HCl, NSC 291565

Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vascular smooth muscle cells. A lack of intracellular calcium prevents uterine myometrial contractions. In addition, this agent may directly inactivate myosin light chain kinase, a critical enzyme necessary for the initiation of muscle contractions.

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Ritodrine hydrochloride Chemical Structure

Ritodrine hydrochloride, CAS 23239-51-2

Pack Size	Availability	Price/USD
100 mg	In stock	$ 58.00
200 mg	In stock	$ 105.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 99.89%

Purity: 99%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	DU21220, Ritodrine HCl, NSC 291565
Molecular Weight	323.82
Formula	C17H21NO3·HCl
CAS No.	23239-51-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 200.7 mM

DMSO: 200.7 mM

References and Literature

1. Tanaka N, et al. J Med Chem. 2001 Apr 26;44(9):1436-45.

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Anti-Cancer Approved Drug Library Drug Repurposing Compound Library Anti-Neurodegenerative Disease Compound Library Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Membrane Protein-targeted Compound Library FDA-Approved Drug Library Adrenergic Receptor-Targeted Compound Library FDA-Approved & Pharmacopeia Drug Library

Related Products

Related compounds with same targets

nifenalol.HCl Clorprenaline hydrochloride Yohimbine Zotepine Phenylephrine Rilmenidine Phosphate Brimonidine Tartrate Salbutamol hemisulfate

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ritodrine hydrochloride 23239-51-2 GPCR/G Protein Neuroscience Adrenergic Receptor Ritodrine DU21220 Beta Receptor Inhibitor Ritodrine HCl Ritodrine Hydrochloride inhibit NSC-291565 NSC 291565 DU 21220 NSC291565 DU-21220 inhibitor

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