Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.
Pack Size | Availability | Price/USD | Quantity |
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2 mg | 5 days | $ 49.00 |
Description | Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM. |
Targets&IC50 | PDE4:2.0 μM, PDE4:3.1 μM(Ki) |
In vivo | RO-20-1724 was found to not only improve learning and memory in MWM and PA paradigms but also restore STZ induced elevation in cholinesterase activity. Further, RO-20-1724 significantly reduced malondialdehyde and nitrite levels, and restored the glutathione levels indicating attenuation of oxidative stress[2]. |
Synonyms | Ro-20-1724, 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone, Ro20-1724 |
Molecular Weight | 278.35 |
Formula | C15H22N2O3 |
CAS No. | 29925-17-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/Ml(179.63 mM)
Ethanol: 50 mg/Ml(179.63 mM)
You can also refer to dose conversion for different animals. More
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Ro 20-1724 29925-17-5 Metabolism PDE neuroprotective Ro 201724 Ro-20-1724 Ro 20-174 Ro 20 1724 phosphodiesterase cognitive cAMP antioxidant 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone inhibit Inhibitor Phosphodiesterase (PDE) Ro20-1724 inhibitor