Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used to facilitate endotracheal intubation and to provide skeletal muscle relaxation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 45.00 | |
50 mg | In stock | $ 61.00 | |
100 mg | In stock | $ 81.00 | |
200 mg | In stock | $ 105.00 | |
500 mg | In stock | $ 142.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used to facilitate endotracheal intubation and to provide skeletal muscle relaxation. |
In vitro | Rocuronium reduced the indirectly elicited twitch tensions in normal (IC50: 9.84 μM) and all pretreated diaphragms (P < .01, n = 6) in a concentration-dependent fashion [1]. The ED95 of rocuronium is essentially the same for children as for adults. Its duration of action is similar to vecuronium, and it is shorter for children than for adults. Rocuronium is readily reversed with conventional doses of cholinesterase-inhibiting drugs [2]. Onset time until maximum block, duration until 25% recovery of twitch height, and recovery from 25 until 75% of twitch height were 1.7 (32), 53 (19) and 20 (37) min, respectively [3]. |
Synonyms | ORG 9426, ORG 9426 (Bromide) |
Molecular Weight | 609.68 |
Formula | C32H53BrN2O4 |
CAS No. | 119302-91-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 113 mg/mL (185.3 mM)
H2O: 112 mg/mL (183.7 mM)
Ethanol: 113 mg/mL (185.3 mM)
You can also refer to dose conversion for different animals. More
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Rocuronium bromide 119302-91-9 Neuroscience AChR Rocuronium Bromide Rocuronium ORG9426 ORG 9426 ORG-9426 Inhibitor inhibit ORG 9426 (Bromide) inhibitor