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Rosiglitazone maleate

Catalog No. T1622 CAS 155141-29-0

Synonyms: BRL 49653C, BRL 49653

Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.

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Rosiglitazone maleate Chemical Structure

Rosiglitazone maleate, CAS 155141-29-0

Pack Size	Availability	Price/USD
25 mg	In stock	$ 36.00
50 mg	In stock	$ 52.00
100 mg	In stock	$ 84.00
200 mg	In stock	$ 150.00
500 mg	In stock	$ 249.00
1 mL * 10 mM (in DMSO)	In stock	$ 39.00

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Purity: 99.33%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.
Targets&IC50	PPARγ:42 nM
In vivo	In numerous cell lines, Rosiglitazone has been found to inhibit cholesterol synthesis. It activates the AMP-activated protein kinase (AMPK) complex, which includes the α1 and α2 subunits within the AMPKα subunit, leading to an increase in phosphorylation.

Synonyms	BRL 49653C, BRL 49653
Molecular Weight	473.5
Formula	C22H23N3O7S
CAS No.	155141-29-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 87 mg/mL (183.9 mM)

H2O: < 1 mg/mL (insoluble or slightly soluble)

References and Literature

1. Deeks ED, et al. Drugs, 2007, 67(18), 2747-2779.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Approved Drug Library EMA Approved Drug Library Anti-Cancer Active Compound Library Anti-Neurodegenerative Disease Compound Library Anti-Cancer Drug Library Drug Repurposing Compound Library Anti-Cancer Clinical Compound Library Stem Cell Differentiation Compound Library FDA-Approved Drug Library Anti-Aging Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

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