Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5. Roslin 2 bromide exhibits anticancer effects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 282.00 | |
25 mg | In stock | $ 497.00 | |
50 mg | In stock | $ 723.00 | |
100 mg | In stock | $ 987.00 | |
500 mg | In stock | $ 1,980.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 198.00 |
Description | Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5. Roslin 2 bromide exhibits anticancer effects. |
In vitro | Roslin 2 bromide decreases cancer cell viability and clonogenicity in a p53-dependent manner[1]. |
In vivo | Roslin 2 bromide (60 mg/kg; i.p) significantly decreased tumor growth, disrupts the complex of FAK and p53, and up-regulated p21 in HCT116 p53+/+ but not in HCT116 p53-/- xenografts[1]. |
Synonyms | Roslin-2, Benzylhexamethylenetetramine bromide, Roslin2 |
Molecular Weight | 311.22 |
Formula | C13H19BrN4 |
CAS No. | 29574-21-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (144.59 mM)
You can also refer to dose conversion for different animals. More
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Roslin 2 bromide 29574-21-8 Angiogenesis Apoptosis Cytoskeletal Signaling Tyrosine Kinase/Adaptors FAK p53 anticancer effect Inhibitor Roslin-2 Roslin 2 Bromide Roslin 2 Focal adhesion kinase Benzylhexamethylenetetramine PTK2 MDM-2/p53 inhibit PTK2 protein tyrosine kinase 2 Benzylhexamethylenetetramine bromide Roslin2 p53 reactivator Benzylhexamethylenetetramine Bromide inhibitor