Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis. Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells. Rosmanol has anti-inflammatory activity, it potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3 and C/EBP signaling pathways.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 68.00 | |
5 mg | In stock | $ 147.00 | |
10 mg | In stock | $ 228.00 | |
25 mg | In stock | $ 478.00 | |
50 mg | In stock | $ 688.00 | |
100 mg | In stock | $ 957.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 162.00 |
Description | Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis. Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells. Rosmanol has anti-inflammatory activity, it potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3 and C/EBP signaling pathways. |
Source |
Molecular Weight | 346.42 |
Formula | C20H26O5 |
CAS No. | 80225-53-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chloroform: Soluble
DMSO: 60 mg/ml (173.2 mM)
You can also refer to dose conversion for different animals. More
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Rosmanol 80225-53-2 Immunology/Inflammation Neuroscience oxidation-reduction Antioxidant COX Inhibitor inhibit inhibitor