store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 117.00 | |
5 mg | In stock | $ 297.00 | |
10 mg | In stock | $ 513.00 | |
25 mg | In stock | $ 819.00 | |
50 mg | In stock | $ 1,090.00 | |
100 mg | In stock | $ 1,490.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 282.00 |
Description | SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively. |
Targets&IC50 | 5-HT2C receptor:9 (pki), 5-HT2A receptor:6.9 (pki), 5-HT2B receptor:8 (pki) |
In vivo | In male Sprague Dawley rats, oral administration of SB228357 (0-10 mg/kg) reverses Haloperidol-induced catalepsy obviously[2]. |
Molecular Weight | 431.38 |
Formula | C22H17F4N3O2 |
CAS No. | 181629-93-6 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 38.9 mg/mL (90.1 mM)
You can also refer to dose conversion for different animals. More
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SB228357 181629-93-6 GPCR/G Protein Neuroscience 5-HT Receptor SB-228357 SB 228357 inhibitor inhibit