Powder: -20°C for 3 years
In solvent: -80°C for 2 years
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
Description | SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively. |
Targets&IC50 | 5-HT2B Receptor:8 (pki), 5-HT2A Receptor:6.9 (pki), 5-HT2C Receptor:9 (pki) |
In vivo | In male Sprague Dawley rats, oral administration of SB228357 (0-10 mg/kg) reverses Haloperidol-induced catalepsy obviously[2]. |
Molecular Weight | 431.391 |
Formula | C22H17F4N3O2 |
CAS No. | 181629-93-6 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 38.9 mg/mL (90.1 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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SB228357 181629-93-6 G蛋白偶联受体 神经科学 5-HT Receptor SB-228357 Inhibitor inhibitor inhibit