Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SNIPER(BRD)-1 is a chemical compound composed of a derivative of the IAP antagonist LCL-161 and the BET inhibitor (+)-JQ-1, linked together. It promotes the degradation of BRD4 through the ubiquitin-proteasome pathway and effectively degrades cIAP1, cIAP2, and XIAP with IC50 values of 6.8 nM, 17 nM, and 49nM, respectively[1].
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Description | SNIPER(BRD)-1 is a chemical compound composed of a derivative of the IAP antagonist LCL-161 and the BET inhibitor (+)-JQ-1, linked together. It promotes the degradation of BRD4 through the ubiquitin-proteasome pathway and effectively degrades cIAP1, cIAP2, and XIAP with IC50 values of 6.8 nM, 17 nM, and 49nM, respectively[1]. |
Targets&IC50 | CIAP2:17 nM, XIAP:49 nM (ki), CIAP1:6.8 nM, SNIPER: |
Molecular Weight | 1056.73 |
Formula | C53H66ClN9O8S2 |
CAS No. | 2095244-54-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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SNIPER(BRD)-1 2095244-54-3 Others SNIPER(BRD)1 SNIPER(BRD) 1 inhibitor inhibit