store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Safranal is the special volatile aroma compound of saffron.Safranal has neuroprotective and anti-inflammatory effects and has the potential for Parkinson’s disease research.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 41.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Safranal is the special volatile aroma compound of saffron.Safranal has neuroprotective and anti-inflammatory effects and has the potential for Parkinson’s disease research. |
In vitro | At first, the potential toxic effect of safranal on OLN-93 viability was evaluated. Also, the cells were pretreated with safranal (0.1, 1, 10, 50, 100 and 200 μM) for 2 h and then subjected to glutamic acid (16 mM) or quinolinic acid (8 mM) toxicity for 24 h, in which the same treatments were applied. Results: Safranal at concentration ranges of 1-800 μM had no toxic effect on cell viability (p>0.05). Treatment with safranal significantly increased cell viability following glutamic acid or quinolinic acid insults at concentrations higher than 1 μM (p<0.01). The cytoprotective potential of safranal was also accompanied by decreased ROS accumulation (p<0.001) and malondialdehyde level (p<0.001) following glutamic acid or quinolinic acid insults. The data suggests that safranal exhibits oligoprotection potential by means of inhibiting oxidative stress parameters. |
In vivo | Safranal (200-500 mg/kg; PO; for 7 days) causes a slight restoration of colon length and percentage of weight loss, and the DAI score is significantly low[2]. |
Source |
Molecular Weight | 150.22 |
Formula | C10H14O |
CAS No. | 116-26-7 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (665.69 mM), sonification is recommended.
Ethanol: 100 mg/mL (665.69 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Safranal 116-26-7 oxidation-reduction Antioxidant disease inhibit anti-inflammatory Saffron Inhibitor Parkinson’s neuroprotective orally inhibitor