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Sanguinarine chloride

Catalog No. T0129   CAS 5578-73-4
Synonyms: Pseudochelerythrine chloride, Sanguinarium chloride

Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygen species (ROS).

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Sanguinarine chloride Chemical Structure
Sanguinarine chloride, CAS 5578-73-4
Pack Size Availability Price/USD Quantity
20 mg In stock $ 50.00
1 mL * 10 mM (in DMSO) In stock $ 50.00
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Purity: 99.33%
Purity: 99.33%
Purity: 98.91%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygen species (ROS).
Targets&IC50 PP2C:0.68 μM(Ki)
Source
Synonyms Pseudochelerythrine chloride, Sanguinarium chloride
Molecular Weight 367.78
Formula C20H14ClNO4
CAS No. 5578-73-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 3.7 mg/mL(10 mM)

TargetMolReferences and Literature

1. Han MH, et al.Toxicol Lett. 2013 Jul 4;220(2):157-66.

TargetMolCitations

1. Liang X, Cao Y, Duan Z, et al.Discovery of New Small Molecule Inhibitors of the BPTF Bromodomain.Bioorganic Chemistry.2023: 106453. 2. Liu S, Tao Y, Wu S, et al.Sanguinarine chloride induces ferroptosis by regulating ROS/BACH1/HMOX1 signaling pathway in prostate cancer.Chinese Medicine.2024, 19(1): 1-18.

Related compound libraries

This product is contained In the following compound libraries:
Tyrosine Kinase Inhibitor Library Anti-Cancer Drug Library Anti-Parasitic Compound Library Anti-Cancer Approved Drug Library Antiparasitic Natural Product Library Anti-Inflammatory Traditional Chinese Medicine Compound Library Anti-Cardiovascular Disease Compound Library RO5 Drug-like Natural Product Library Angiogenesis related Compound Library Anti-Liver Cancer Compound Library

Related Products

Related compounds with same targets
GPNA hydrochloride AGK2 Neobavaisoflavone Betulinic acid Methyl-4-oxoretinoate Ethoxysanguinarine Evofosfamide Eprenetapopt

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Keywords

Sanguinarine chloride 5578-73-4 Angiogenesis Apoptosis Autophagy JAK/STAT signaling Microbiology/Virology Tyrosine Kinase/Adaptors EGFR VEGFR Antibacterial Parasite Bacterial Sanguinarin Pseudochelerythrine chloride Sanguinarine Chloride inhibit Sanguinarine Sanguinarium Chloride Pseudochelerythrine Inhibitor Sanguinarium Sanguinarium chloride Pseudochelerythrine Chloride inhibitor

 

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