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Secoisolariciresinol

Catalog No. TN2197 CAS 29388-59-8

Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation in 3T3-L1 adipocytes.

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Secoisolariciresinol, CAS 29388-59-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 129.00
5 mg	In stock	$ 320.00
10 mg	In stock	$ 475.00
25 mg	In stock	$ 779.00
50 mg	In stock	$ 1,090.00
100 mg	In stock	$ 1,470.00
1 mL * 10 mM (in DMSO)	In stock	$ 330.00

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Purity: 99.51%

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Description	Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation in 3T3-L1 adipocytes.
In vitro	The effects of SECOs on the regulation of 3T3-L1 adipocytes, and identified the structure-activity relationships. Optically active SECO and meso-SECO were tested for their effects on lipid metabolism in 3T3-L1 adipocytes. (-)-SECO accelerated adiponectin production of 3T3-L1 adipocytes. On the other hand, (+)- and meso-SECO suppressed the production of adiponectin. In addition, triglyceride (TG) accumulation in 3T3-L1 adipocytes was significantly suppressed by all three SECOs tested here, as was 17beta-estradiol, when the SECOs were added to the medium during induction of 3T3-L1 preadipocytes to adipocytes. Especially, (-)-SECO strongly reduced TG accumulation[1]
Source	Natural Products > Podocarpaceae > Podocarpus

Molecular Weight	362.42
Formula	C20H26O6
CAS No.	29388-59-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 30 mg/mL (82.78 mM)

References and Literature

1. The Effect of Secoisolariciresinol on 3T3-L1 Adipocytes and the Relationship between Molecular Structure and Activity.Biosci Biotechnol Biochem. 2009 Jan;73(1):35-9.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Miao medicine Compound Library Tibetan medicine Compound Library Ferroptosis Compound Library Pyroptosis Compound Library RO5 Drug-like Natural Product Library Natural Product Library The Yao nationality medicine Library Human Metabolite Library Anti-Aging Compound Library

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Secoisolariciresinol 29388-59-8 Apoptosis TNF inhibit Inhibitor inhibitor

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