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Sergliflozin etabonate

Catalog No. T28757 CAS 408504-26-7

Synonyms: GW-869682, GW-869682X, KGT-1251, GW869682X, GW869682, KGT1251

Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Sergliflozin etabonate Chemical Structure

Sergliflozin etabonate, CAS 408504-26-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 195.00
2 mg	In stock	$ 293.00
5 mg	In stock	$ 448.00
10 mg	In stock	$ 658.00
25 mg	In stock	$ 987.00
50 mg	In stock	$ 1,380.00
100 mg	In stock	$ 1,890.00
1 mL * 10 mM (in DMSO)	In stock	$ 516.00

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Purity: 95.59%

Biological Description

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Description

Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.

Synonyms	GW-869682, GW-869682X, KGT-1251, GW869682X, GW869682, KGT1251
Molecular Weight	448.46
Formula	C23H28O9
CAS No.	408504-26-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (111.49 mM)

References and Literature

1. Hussey EK, et al. Multiple-dose pharmacokinetics and pharmacodynamics of sergliflozin etabonate, a novel inhibitor of glucose reabsorption, in healthy overweight and obese subjects: a randomized double-blind study. J Clin Pharmacol. 2010 Jun;50(6):636-46. 2. Katsuno K, et al. Long-term treatment with sergliflozin etabonate improves disturbed glucose metabolism in KK-A(y) mice. Eur J Pharmacol. 2009 Sep 15;618(1-3):98-104. 3. Fujimori Y, et al. Sergliflozin etabonate, a selective SGLT2 inhibitor, improves glycemic control in streptozotocin-induced diabetic rats and Zucker fatty rats. Eur J Pharmacol. 2009 May 1;609(1-3):148-54. 4. Hussey EK, et al. Single-dose pharmacokinetics and pharmacodynamics of sergliflozin etabonate, a novel inhibitor of glucose reabsorption, in healthy volunteers and patients with type 2 diabetes mellitus. J Clin Pharmacol. 2010 Jun;50(6):623-35.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library Inhibitor Library Drug Repurposing Compound Library GPCR Compound Library Bioactive Compounds Library Max Clinical Compound Library ReFRAME Related Library Bioactive Compound Library Anti-Obesity Compound Library

Related Products

Related compounds with same targets

Sotagliflozin SGLT inhibitor-1 HSK0935 Velagliflozin SGL5213 Picraline Licogliflozin LY2794193

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Sergliflozin etabonate 408504-26-7 GPCR/G Protein SGLT GW-869682 GW-869682X KGT-1251 GW 869682 GW869682X GW869682 KGT 1251 KGT1251 inhibitor inhibit

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