Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solabegron (GW 427353) is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR(EC50 : 22 nM). It is used for treatment of overactive bladder and irritable bowel syndrome.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 89.00 | |
5 mg | In stock | $ 278.00 | |
10 mg | In stock | $ 455.00 | |
25 mg | In stock | $ 828.00 | |
50 mg | In stock | $ 1,120.00 | |
100 mg | In stock | $ 1,490.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 297.00 |
Description | Solabegron (GW 427353) is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR(EC50 : 22 nM). It is used for treatment of overactive bladder and irritable bowel syndrome. |
Targets&IC50 | β3-adrenoceptor:(EC50)22 Nm |
In vivo | Solabegron(3 mg/kg i.v.)evokes an increase in micturition volume threshold that prevented the acetic acid-evoked decreases in dogs. |
Synonyms | GW 427353 |
Molecular Weight | 410.89 |
Formula | C23H23ClN2O3 |
CAS No. | 252920-94-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (608.44 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Solabegron 252920-94-8 GPCR/G Protein Neuroscience Adrenergic Receptor inhibit Inhibitor GW 427353 GW427353 Beta Receptor GW-427353 inhibitor