Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sulfinpyrazone (NSC-75925) is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 43.00 | |
200 mg | In stock | $ 58.00 | |
500 mg | In stock | $ 93.00 | |
1 g | In stock | $ 135.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | Sulfinpyrazone (NSC-75925) is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties. |
In vivo | Sulfinpyrazone exerts significant electrophysiologic actions under various experimental conditions. It raises the ventricular fibrillation threshold as well as the mid diastolic threshold and prolongs the effective refractory period. In the acutely ischemic heart, it attenuates the effect of coronary occlusion on the ventricular fibrillation threshold but has no effect after reperfusion. A protective influence of the drug is also evident during sympathetic humoral stimulation with norepinephrine. The antifibrillatory effect of sulfinpyrazone is additive to the changes elicited by beta adrenergic blockade with practolol or cardiac membrane stabilization with lidocaine[1]. |
Synonyms | (+/-)-Sulfinpyrazone, G-28315, NSC 75925 |
Molecular Weight | 404.48 |
Formula | C23H20N2O3S |
CAS No. | 57-96-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 64 mg/mL (158.23 mM)
DMSO: 73 mg/mL(180.5 mM)
You can also refer to dose conversion for different animals. More
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Sulfinpyrazone 57-96-5 Immunology/Inflammation Neuroscience COX gouty (+/-)-Sulfinpyrazone G28315 uricosuric intermittent antithrombotic G 28315 oral G-28315 arthritis platelet NSC-75925 inhibit NSC 75925 NSC75925 Inhibitor inhibitor