Powder: -20°C for 3 years | In solvent: -80°C for 1 year
T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta(PI4KIIIβ, IC50 = 60 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 51.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 197.00 | |
25 mg | In stock | $ 395.00 | |
50 mg | In stock | $ 589.00 | |
100 mg | In stock | $ 843.00 | |
500 mg | In stock | $ 1,730.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 259.00 |
Description | T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta(PI4KIIIβ, IC50 = 60 nM). |
Targets&IC50 | Anti-poliovirus (PV):0.77 μM(EC50), PI4KIIIβ:60 nM |
In vitro | T-00127_HEV1 displays a more potent anti-poliovirus activity (EC50: 0.77 μM) than other candidate compounds (EC50: 1.7 to 4.7 μM). GW5074 and T-00127_HEV1 almost fully inhibit PI4KB kinase activity at 10 μM (3% and 5% of residual activity, respectively), in contrast to AN-12-H5 (108% of activity [no inhibition]) [1]. |
Molecular Weight | 411.5 |
Formula | C22H29N5O3 |
CAS No. | 900874-91-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6 mg/ml (14.58 mM), Sonification is recommended
You can also refer to dose conversion for different animals. More
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T-00127_HEV1 900874-91-1 PI3K/Akt/mTOR signaling PI4K PI4 kinases Inhibitor Phosphatidylinositol 4 kinases T00127_HEV1 inhibit T-00127_HEV-1 T 00127_HEV1 inhibitor