Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
2 mg | In stock | $ 147.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 397.00 | |
25 mg | In stock | $ 663.00 | |
50 mg | In stock | $ 945.00 | |
100 mg | In stock | $ 1,280.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 272.00 |
Description | TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T |
Targets&IC50 | PI3Kγ:29 nM (IC50), Akt:294 nM (IC50) |
In vivo | TASP0415914 demonstrated good potency in a cell-based assay and, furthermore, exhibited in vivo efficacy in a collagen induced arthritis (CIA) model in mice after oral administration[1]. |
Molecular Weight | 323.37 |
Formula | C13H17N5O3S |
CAS No. | 1292300-75-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11 mg/mL (34.02 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TASP0415914 1292300-75-4 Cytoskeletal Signaling PI3K/Akt/mTOR signaling Akt PI3K inhibit inflammatory PKB stability PI3Kγ oral TASP-0415914 Phosphoinositide 3-kinase Protein kinase B Inhibitor autoimmune TASP 0415914 metabolic inhibitor